pH-Dependent Electrophoretic Separation of
Hb A
from
Hb S
Paper Electrophoresis of an Equal Molar Mixture of
Normal Adult Hemoglobin (
Hb A
) and Mutant Sickle-Cell Hemoglobin (
Hb S
)
Normal Adult Hb A: pI(Hb A)
=
6.87
Sickle Cell Hb S: pI(Hb S) = 7.09
pI(Hb A)
<
pI(Hb S)
©
Duane W. Sears
and Erin M. Hildebrand, Revised: January 26, 2021
